Stroke Therapy in Patients Considering Prothrombin Time and International Normalized Ratio
نویسندگان
چکیده
منابع مشابه
Stroke therapy in patients considering prothrombin time and international normalized ratio.
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International normalized ratio (INR) monitoring is essential during oral anticoagulation therapy to minimize bleeding complications and thrombotic events. Laboratory technicians cannot differentiate falsely elevated INR results due to problems in drawing blood from truly elevated INR values, but the extent of this phenomenon is unclear. We determined the proportion of patients with INR values o...
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Despite careful monitoring of oral anticoagulant treatment (OAT), some international normalized ratio (INR) for prothrombin time values will fall outside the therapeutic range. Considerable changes in serial INR results from OAT patients may be caused by random fluctuation alone, and, for statistical reasons, a fraction of the INR values will fall outside therapeutic range and interfere with do...
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The FDA has become aware of performance problems associated with point of care (POC) Prothrombin Time (PT)/International Normalized Ratio (INR) devices that raise patient safety concerns. Numerous reports of serious adverse events for POC PT/INR devices have been submitted to the FDA. The FDA’s postmarket analysis of these reports indicates that the adverse events appear to be linked to inaccur...
متن کاملPoor agreement among prothrombin time international normalized ratio methods: comparison of seven commercial reagents.
BACKGROUND Prothrombin time (PT) has long been the most popular test for monitoring oral anticoagulation therapy. The International Normalized Ratio (INR) was introduced to overcome the problem of marked variation in PT results among laboratories and the various recommendations for patient care. According to this principle, all reagents should be calibrated to give identical results and the sam...
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ژورنال
عنوان ژورنال: Stroke
سال: 2010
ISSN: 0039-2499,1524-4628
DOI: 10.1161/strokeaha.110.579771